They don't hurt but they are a pain in the butt.
The hospital sent me home with a spreadsheet to keep track of the amount of fluid that drains from each tube. I was told that the drains need to stay in for about 10 days. My drains were in for 22 days. Yes, that means no shower for 22 days. The risk of infection is too great.
I didn't like the spreadsheet that was given to me, so I created a better one. :)
Feel free to download my drainage chart if you or someone you know should need one.
Removing the drains didn't hurt, just felt a bit odd because I could feel the long tube on the inside, being pulled to the outside. YUCK!
And if you have experience with drains, please feel free to add your story in the comments below. I remember it being very helpful to me when I was searching the internet, to find several stories of experience.